1-Methyl-4-(piperidin-4-yl)piperazine → 1-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-2-(5,6,7,8-tetrahydro-naphthalen-2-ylmethyl)-butan-1,4-dione
Reaktionsgleichung
[CH3:36][N:37]1[CH2:38][CH2:39][N:40]([CH:43]2[CH2:44][CH2:45][NH:46][CH2:47][CH2:48]2)[CH2:41][CH2:42]1.[O:1]=[C:2]([CH2:3][CH:4]([C:5](=[O:6])[OH:7])[CH2:8][c:9]1[cH:10][c:11]2[c:16]([cH:17][cH:18]1)[CH2:15][CH2:14][CH2:13][CH2:12]2)[N:19]1[CH2:20][CH2:21][CH:22]([N:25]2[C:26](=[O:35])[NH:27][c:28]3[cH:29][cH:30][cH:31][cH:32][c:33]3[CH2:34]2)[CH2:23][CH2:24]1>>[O:1]=[C:2]([CH2:3][CH:4]([C:5](=[O:6])[N:46]1[CH2:45][CH2:44][CH:43]([N:40]2[CH2:39][CH2:38][N:37]([CH3:36])[CH2:42][CH2:41]2)[CH2:48][CH2:47]1)[CH2:8][c:9]1[cH:10][c:11]2[c:16]([cH:17][cH:18]1)[CH2:15][CH2:14][CH2:13][CH2:12]2)[N:19]1[CH2:20][CH2:21][CH:22]([N:25]2[C:26](=[O:35])[NH:27][c:28]3[cH:29][cH:30][cH:31][cH:32][c:33]3[CH2:34]2)[CH2:23][CH2:24]1Komponenten
3
Edukt 2
Produkt 1
Quellen und Nachweise
- ORD-Eintrag
- ord-6048540ed5e940cba2f0682c62803bf3
- Quelldatensatz
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)