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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 12347Erstellt: 24. Oktober 2026

O-Methyltyramine → 8-Indan-5-yl-2-(2-(4-methoxy-phenyl)-ethylamino)-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

https://huagongshe.com/de/reaction/12347

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktO-MethyltyramineHCID 4657—
Edukt8-Indan-5-yl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl esterHCID 25222982—
Produkt8-Indan-5-yl-2-(2-(4-methoxy-phenyl)-ethylamino)-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl esterHCID 68583341—

Reaktionsschritte

Using the procedure outlined in Example 1 Step F, the title compound was prepared from 2-(4-methoxy-phenyl)-ethylamine and 8-indan-5-yl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester (Example 1 Step E, 20 mg, 0.040 mmol). 16 mg of 8-Indan-5-yl-2-(2-(4-methoxy-phenyl)-ethylamino)-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester was obtained as a white solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07728003B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-919543a4f7864fcdaad14c824ac2a07e
Quellennotizuspto-grants-2010_06