HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
O-Methyltyramine → 8-Indan-5-yl-2-(2-(4-methoxy-phenyl)-ethylamino)-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | O-Methyltyramine | HCID 4657 | — |
| Edukt | 8-Indan-5-yl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester | HCID 25222982 | — |
| Produkt | 8-Indan-5-yl-2-(2-(4-methoxy-phenyl)-ethylamino)-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester | HCID 68583341 | — |
Reaktionsschritte
Using the procedure outlined in Example 1 Step F, the title compound was prepared from 2-(4-methoxy-phenyl)-ethylamine and 8-indan-5-yl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester (Example 1 Step E, 20 mg, 0.040 mmol). 16 mg of 8-Indan-5-yl-2-(2-(4-methoxy-phenyl)-ethylamino)-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester was obtained as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07728003B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-919543a4f7864fcdaad14c824ac2a07e |
| Quellennotiz | uspto-grants-2010_06 |