Dichloromethane → 1-[1-[3-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-2-hydroxy-propyl]-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl]-ethanone
Reaktionsgleichung
[C:1]([O:2][C:6](=[O:3])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][o:16][c:17]3[c:18]2[cH:19][cH:20][cH:21][cH:22]3)[CH2:12][CH2:13]1)([CH3:4])([CH3:5])[CH3:7].[Cl:56][CH2:57][Cl:58].[O:30]1[CH:31]([CH2:33][n:34]2[n:35][c:36](-[c:46]3[cH:47][cH:48][c:49]([C:52]([F:53])([F:54])[F:55])[cH:50][cH:51]3)[c:37]3[c:42]2[CH2:41][CH2:40][N:39]([C:43]([CH3:44])=[O:45])[CH2:38]3)[CH2:32]1.[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[CH2:6]([N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][o:16][c:17]3[c:18]2[cH:19][cH:20][cH:21][cH:22]3)[CH2:12][CH2:13]1)[CH:31]([OH:30])[CH2:33][n:34]1[n:35][c:36](-[c:46]2[cH:47][cH:48][c:49]([C:52]([F:53])([F:54])[F:55])[cH:50][cH:51]2)[c:37]2[c:42]1[CH2:41][CH2:40][N:39]([C:43]([CH3:44])=[O:45])[CH2:38]2
