Hydrochloric Acid → HCID 131723149, Verbindung

HRID 1245579Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1245579
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([C:14]2[N:18]([CH2:19][CH3:20])[N:17]=[C:16]([CH2:21][CH3:22])[C:15]=2[CH3:23])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:24]>CO>[ClH:24].[ClH:24].[CH2:19]([N:18]1[C:14]([CH:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)=[C:15]([CH3:23])[C:16]([CH2:21][CH3:22])=[N:17]1)[CH3:20]

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 21912727HCID 21912727, Verbindung

Produkt 1

HCID 131723149HCID 131723149, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

A solution of 1-(tert-butoxycarbonyl)-4-(1,3-diethyl-4-methyl-(1H)-pyrazol-5-yl)piperidine (348 mg) (from Step E) in 2.5 N HCl in methanol was stirred at rt for 16 h. The solution was concentrated and the resulting solid was suspended in ethyl acetate, filtered and dried to afford the title compound.

Aufarbeitung

  1. concentrationThe solution was concentrated
  2. filtrationfiltered
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-e86fe8f6a67f46659527905dc36418a0
Quelldatensatz
uspto-grants-2006_10
Patentnummer
US07125887B2

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