Thionyl Chloride → HCID 10355913, Verbindung
Reaktionsgleichung
[CH2:1]([O:5][C:6]1[C:14]([O:15][CH3:16])=[CH:13][C:9]([C:10](O)=[O:11])=[CH:8][C:7]=1[O:17][CH3:18])[CH2:2][CH2:3][CH3:4].S(Cl)([Cl:21])=O>C1(C)C=CC=CC=1>[CH2:1]([O:5][C:6]1[C:14]([O:15][CH3:16])=[CH:13][C:9]([C:10]([Cl:21])=[O:11])=[CH:8][C:7]=1[O:17][CH3:18])[CH2:2][CH2:3][CH3:4]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 90 °C
Versuchsvorschrift
A mixture of 4-butyloxy-3,5-dimethoxybenzoic acid (5.0 g, 0.0197 mol) and thionyl chloride (10 mL) in toluene (10 mL) was heated at 90° C. for 18 h. The reaction mixture was concentrated under reduced pressure. To remove excess of thionyl chloride the residue was repeatedly redissolved in toluene (3×20 mL) and the resulting solution evaporated to dryness to obtain 4-butyloxy-3,5-dimethoxybenzoyl chloride (5.3 g, 99% yield) as a pale yellow oil. 1H NMR (CDCl3) δ: 0.99 (t, J=5.0 Hz, 3H), 1.47 (m, 2H), 1.73 (m, 2H), 3.90 (s, 6H), 4.09 (t, J=5.1 Hz, 2H), 7.36 (s, 2H).