4-(Aminomethyl)-3-chlorobenzonitrile → (RS)-N-(2-chloro-4-cyano-benzyl)-2-(2,6-difluoro-4-methoxy-phenyl)-2-ethoxy-acetamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-(Aminomethyl)-3-chlorobenzonitrile	HCID 4089788	—
Edukt	(RS)-(2,6-Difluoro-4-methoxy-phenyl)-ethoxy-acetic acid	HCID 21905754	—
Produkt	(RS)-N-(2-chloro-4-cyano-benzyl)-2-(2,6-difluoro-4-methoxy-phenyl)-2-ethoxy-acetamide	HCID 21905488	—

Reaktionsschritte

(RS)-(2,6-Difluoro-4-methoxy-phenyl)-ethoxy-acetic acid was coupled with 4-aminomethyl-3-chlorobenzonitrile (CAS 202521-97-9) according to general procedure C to give (RS)-N-(2-chloro-4-cyano-benzyl)-2-(2,6-difluoro-4-methoxy-phenyl)-2-ethoxy-acetamide. Colorless oil. MS 395.0 ([M+H]+)

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07129238B2
Quelldatensatz	uspto-grants-2006_10
ORD ID	ord-900b769329394c4f8fc1a4bf56a2a211
Quellennotiz	uspto-grants-2006_10