Ethylenediamine → 6-[3-bromo-4-(1,3-diazacyclopenten-2-ylamino)-phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone

HRID 1247887

Reaktionsgleichung

Reaktionsgleichung von HRID 1247887
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]([CH3:15])[CH2:10][C:11](=[O:14])[NH:12][N:13]=2)=[CH:4][C:3]=1[Br:16].CS[N:19]=[C:20]=O.[CH2:22](N)[CH2:23][NH2:24]>>[Br:16][C:3]1[CH:4]=[C:5]([C:8]2[CH:9]([CH3:15])[CH2:10][C:11](=[O:14])[NH:12][N:13]=2)[CH:6]=[CH:7][C:2]=1[NH:1][C:20]1[NH:19][CH2:22][CH2:23][N:24]=1

Komponenten

4

Edukt 3

HCID 3301EthylenediamineHCID 202792156-(4-Amino-3-bromophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-oneHCID 21933440Methylthioisocyanate

Produkt 1

HCID 132173476-[3-bromo-4-(1,3-diazacyclopenten-2-ylamino)-phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone

Versuchsvorschrift

Using 6-(4-amino-3-bromophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone and methylthioisocyanate, the reaction was carried out in the same manner as described in Example 1(b) to the corresponding methylisothiuronium salt which was then reacted with ethylenediamine in the same manner as described in Example 1(c) to afford the above-identified compound. M.P. 265°-267° C. (with decomp.).

Aufarbeitung

  1. customto afford the above-identified compound

Quellen und Nachweise

ORD-Eintrag
ord-7edb9ac9cca4413199e59b4400518b73
Quelldatensatz
uspto-grants-1985_06
Patentnummer
US04521415

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