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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1247953Erstellt: 26. Oktober 2026

3-Ethoxy-1-(3-pyridinyl)-2-propen-1-one → Phenyl[7-(3-pyridinyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone

https://huagongshe.com/reaction/1247953

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-Ethoxy-1-(3-pyridinyl)-2-propen-1-oneHCID 54032326—
EduktHCID 178509267HCID 178509267—
LösungsmittelO-XyleneHCID 7237—
ProduktPhenyl[7-(3-pyridinyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanoneHCID 13475883—

Reaktionsschritte

A mixture of 0.02 mole of 3-ethoxy-1-(3-pyridinyl)-2-propen-1-one, 0.02 mole of (3-amino-1H-pyrazol-4-yl)phenyl-methanone and 100 ml of xylene was refluxed for 12 hours. The solvent was removed and the residue dissolved in dichloromethane. This solution was dried over sodium sulfate and the product isolated as described in Example 1, as crystals, mp 202°-203° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04521422
Quelldatensatzuspto-grants-1985_06
ORD IDord-c49638eb094243959a97d943725eda29
Quellennotizuspto-grants-1985_06