HCID 53962035, Verbindung → methyl 4-chloro-1H-indole-2-carboxylate

HRID 1249927Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1249927
[N:1]([C:4](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[Cl:16])[C:5]([O:7][CH3:8])=[O:6])=[N+]=[N-]>C1(C)C=CC=CC=1>[CH3:8][O:7][C:5]([C:4]1[NH:1][C:15]2[C:10]([CH:9]=1)=[C:11]([Cl:16])[CH:12]=[CH:13][CH:14]=2)=[O:6]

Komponenten

3

Edukt 1

HCID 53962035HCID 53962035, Verbindung

Produkt 1

HCID 4714974methyl 4-chloro-1H-indole-2-carboxylate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

Methyl 2-azido-3-(2-chlorophenyl)-propenoate (3.566 g, 144 mmol) was suspended in toluene (800 ml) and the mixture was heated at reflux for three hours, then cooled and allowed to stir at room temperature overnight. A yellow crystalline material was obtained by filtration and recrystallised from hexane.

Aufarbeitung

  1. temperaturethe mixture was heated
  2. temperatureat reflux for three hours
  3. temperaturecooled
  4. customA yellow crystalline material was obtained by filtration
  5. customrecrystallised from hexane

Quellen und Nachweise

ORD-Eintrag
ord-9fbec446f6ef4eada94f1b9e25d08cbe
Quelldatensatz
uspto-grants-2002_01
Patentnummer
US06335360B1

Notizen zur Reaktion

Wird geladen…