1-Benzylpiperazine → 6[4-(Phenylmethyl)-1-piperazinyl]-5,8-quinoxalinedione
Reaktionsgleichung
[N:1]1[C:10]2[C:9](=[O:11])[CH:8]=[CH:7][C:6](=[O:12])[C:5]=2[N:4]=[CH:3][CH:2]=1.[CH2:13]([N:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>O1CCOCC1>[C:14]1([CH2:13][N:20]2[CH2:21][CH2:22][N:23]([C:8]3[C:9](=[O:11])[C:10]4[N:1]=[CH:2][CH:3]=[N:4][C:5]=4[C:6](=[O:12])[CH:7]=3)[CH2:24][CH2:25]2)[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of 160 mg of 5,8-quinoxalinedione and 352 mg of 1-benzylpiperazine in 10 ml of dioxane was stirred or 3 hours. The solvent was then removed and the residue triturated with ether. This solid was collected, washed with ether and dried, giving 110 mg of the desired product, mp 165°-168° C. (dec.).