Carbon Tetrachloride → 1-(p-Chlorophenoxy)-3,3-dimethyl-4-chloro-2-butanone

HRID 1253038

Reaktionsgleichung

Reaktionsgleichung von HRID 1253038
[Cl:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][C:8](=[O:14])[C:9]([CH3:13])([CH3:12])[CH2:10]O)=[CH:4][CH:3]=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(Cl)(Cl)(Cl)[Cl:37]>>[Cl:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][C:8](=[O:14])[C:9]([CH3:13])([CH3:12])[CH2:10][Cl:37])=[CH:4][CH:3]=1

Komponenten

4

Edukt 3

HCID 5943Carbon TetrachlorideHCID 11776TriphenylphosphineHCID 201382891-(p-Chlorophenoxy)-3,3-dimethyl-4-hydroxy-2-butanone

Produkt 1

HCID 201382951-(p-Chlorophenoxy)-3,3-dimethyl-4-chloro-2-butanone

Versuchsvorschrift

Into a 100-ml egg plant type flask were placed 2.4 g of 1-(p-chlorophenoxy)-3,3-dimethyl-4-hydroxy-2-butanone, 2.6 g of triphenylphosphine and 50 ml of carbon tetrachloride, which were then refluxed for 18 hours. The reaction mixture was cooled, the crystals separating out were filtered off, and the filtrate was concentrated in a vacuum. The residue obtained was purified by silica gel column chromatography, giving 1.8 g of the above-identified desired compound.

Aufarbeitung

  1. customInto a 100-ml egg plant type flask were placed
  2. temperatureThe reaction mixture was cooled
  3. customthe crystals separating out
  4. filtrationwere filtered off
  5. concentrationthe filtrate was concentrated in a vacuum
  6. customThe residue obtained
  7. customwas purified by silica gel column chromatography

Quellen und Nachweise

ORD-Eintrag
ord-f8e4ddd6dd9644e38fd966178d844820
Quelldatensatz
uspto-grants-1988_05
Patentnummer
US04746673

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