4-Pyridinylacetone → 2,6-Difluoro-N-(4-methyl-5-pyridin-4-yl-thiazol-2-yl)-benzamide
Reaktionsgleichung
[F:1][C:2]1[CH:22]=[CH:21][CH:20]=[C:19]([F:23])[C:3]=1[C:4]([NH:6][C:7]1[S:8][C:9]([C:13]2[CH:14]=NC=[CH:17][CH:18]=2)=[C:10]([CH3:12])[N:11]=1)=[O:5].[N:24]1C=CC(CC(=O)C)=C[CH:25]=1>>[F:23][C:19]1[CH:20]=[CH:21][CH:22]=[C:2]([F:1])[C:3]=1[C:4]([NH:6][C:7]1[S:8][C:9]([C:13]2[CH:18]=[CH:17][N:24]=[CH:25][CH:14]=2)=[C:10]([CH3:12])[N:11]=1)=[O:5]Komponenten
3
Versuchsvorschrift
Compound 17 was prepared as described for the preparation of Compound 16 using commercially available (4-pyridyl)acetone.
Quellen und Nachweise
- ORD-Eintrag
- ord-e49a0ea1cf4946a5a16b58c1d2bd04cb
- Quelldatensatz
- uspto-grants-2013_06
- Patentnummer
- US08455658B2
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