HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N,N'-Dimethylethylenediamine → 1-[6-Phenyl-5-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-propan-1-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N,N'-Dimethylethylenediamine | HCID 8070 | — |
| Edukt | Triethylaluminum | HCID 16682930 | — |
| Edukt | Ethyl 6-Phenyl-5-(4-trifluoromethylphenyl)-pyridine-2-carboxylate | HCID 68408073 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | 1-[6-Phenyl-5-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-propan-1-one | HCID 59338833 | — |
Reaktionsschritte
Following General Procedure O, 6-phenyl-5-(4-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid ethyl ester (Compound 25, 94 mg, 0.25 mmol) in toluene (3 ml), N,N′-dimethylethylenediamine (DMEDA, 25 mg, 0.28 mmol) and triethylaluminum (0.7 ml, 0.76 mmol, 1 M in hexane) were reacted to produce the title compound as a oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07728014B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-67de139c15fd488b96d4fe1acdce8dbf |
| Quellennotiz | uspto-grants-2010_06 |