HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethyl Sulfoxide → 4-Isopropylcinnamaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethyl Sulfoxide | HCID 679 | — |
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Oxalyl chloride | HCID 65578 | — |
| Edukt | (2E)-3-[4-(Propan-2-yl)phenyl]prop-2-en-1-ol | HCID 21961314 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 4-Isopropylcinnamaldehyde | HCID 5354897 | — |
Reaktionsschritte
Following General Procedure H, oxalyl chloride (9.5 ml, 19.0 mmol, 2M in CH2Cl2), DMSO (1.8 ml, 25.3 mmol), (E)-3-(4-isopropylphenyl)prop-2-en-1-ol (Compound 109, 2.2 g, 12.6 mmol) and triethylamine (7.1 ml, 50.7 mmol) in CH2Cl2 (100 ml) were reacted to obtain the title compound as an oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07728014B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-91fe98f3a159420ea2965d62c2c78fad |
| Quellennotiz | uspto-grants-2010_06 |