Methylamine → 4,5-Dichloro-n-methyl-2-nitroaniline

Beteiligte Stoffe

Reaktionsschritte

1,2-Dichloro-4-fluoro-5-nitrobenzene (5.00 g, 23.8 mmol) in DMF (5.0 mL) was added to methylamine (10% in toluene, 80.0 g, 258 mmol) and stirred at rt overnight. The reaction mixture was filtered through a pad of ALOX B, washed with DMF/MeOH and concentrated to give the sub-title compound.

Herkunft & Nachweise