1,1'-Thiocarbonyldi-2(1H)-pyridone → HCID 86646343, Verbindung

HRID 1258634Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1258634
[C:1](N1C=CC=CC1=O)(N1C=CC=CC1=O)=[S:2].[NH2:17][C:18]1[CH:19]=[C:20]([CH:29]=[CH:30][C:31]=1[Cl:32])[CH2:21][NH:22][C:23](=[O:28])[C:24]([CH3:27])([CH3:26])[CH3:25]>C(Cl)Cl>[Cl:32][C:31]1[CH:30]=[CH:29][C:20]([CH2:21][NH:22][C:23](=[O:28])[C:24]([CH3:27])([CH3:26])[CH3:25])=[CH:19][C:18]=1[N:17]=[C:1]=[S:2]

Komponenten

4

Edukt 2

HCID 8531621,1'-Thiocarbonyldi-2(1H)-pyridoneHCID 66765386N-(3-amino-4-chlorobenzyl)pivalamide

Produkt 1

HCID 86646343HCID 86646343, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

1,1′-Thiocarbonyldi-2-pyridone (2.12 g, 9.1 mmol) was added to a mixture of N-(3-amino-4-chlorobenzyl)-2,2-dimethyl-propionamide (2.00 g, 8.3 mmol) and DCM (60 mL) and stirred at rt for 1.5 h. The mixture was filtered over silica gel. The organic layer was concentrated to give the sub-title compound.

Aufarbeitung

  1. filtrationThe mixture was filtered over silica gel
  2. concentrationThe organic layer was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-7125d667e7ff480ebce03b54f597e544
Quelldatensatz
uspto-grants-2013_06
Patentnummer
US08466186B2

Notizen zur Reaktion

Wird geladen…