Hydrochloric Acid → HCID 178483240, Verbindung
Reaktionsgleichung
C(OC(=O)[NH:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[C:11]([NH:16][C:17]2[NH:21][C:20]3[CH:22]=[C:23]([N:27]4[CH2:31][CH2:30][CH2:29][CH:28]4[CH2:32][N:33]([CH3:35])[CH3:34])[C:24]([Cl:26])=[CH:25][C:19]=3[N:18]=2)[CH:10]=1)(C)(C)C.Cl>C1COCC1>[Cl:15][C:12]1[CH:13]=[CH:14][C:9]([CH2:8][NH2:7])=[CH:10][C:11]=1[NH:16][C:17]1[NH:21][C:20]2[CH:22]=[C:23]([N:27]3[CH2:31][CH2:30][CH2:29][CH:28]3[CH2:32][N:33]([CH3:35])[CH3:34])[C:24]([Cl:26])=[CH:25][C:19]=2[N:18]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
The sub-title compound was prepared from {4-chloro-3-[5-chloro-6-(2-dimethylaminomethyl-pyrrolidin-1-yl)-1H-benzimidazol-2-ylamino]-benzyl}-carbamic acid tert-butyl ester (20 mg, 0.04 mmol) and 6 M aq. HCl-solution (1.0 ml) in THF (2 mL) in analogy to example 3 step (d).