2-Cyano-2-(3,4-dichloro-5(2H)-oxo-2-furyl)acetamide → 5-Chloro-2-imino-1-(3,4,5-trifluorobenzyl)-1,2-dihydropyridine-3-carboxamide hydrochloride
Reaktionsgleichung
[C:1]([CH:3]([CH:7]1[C:11]([Cl:12])=[C:10](Cl)C(=O)O1)[C:4]([NH2:6])=[O:5])#[N:2].[F:15][C:16]1[CH:17]=[C:18]([CH2:24][NH2:25])[CH:19]=[C:20]([F:23])[C:21]=1[F:22]>>[ClH:12].[Cl:12][C:11]1[CH:7]=[C:3]([C:4]([NH2:6])=[O:5])[C:1](=[NH:2])[N:25]([CH2:24][C:18]2[CH:19]=[C:20]([F:23])[C:21]([F:22])=[C:16]([F:15])[CH:17]=2)[CH:10]=1Komponenten
3
Versuchsvorschrift
According to the method of Example 160, 2-cyano-2-(3,4-dichloro-5-oxo-2,5-dihydrofuran-2-yl)acetamide was reacted with 1-(3,4,5-trifluorophenyl)methanamine to give the title compound.
Quellen und Nachweise
- ORD-Eintrag
- ord-74006f09446f484d82e7e5acb4cb7017
- Quelldatensatz
- uspto-grants-2013_06