Thionyl Chloride → HCID 58087452, Verbindung

Reaktionsgleichung

[CH2:1]([S:4]([NH:7][C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11](O)=[O:12])(=[O:6])=[O:5])[CH2:2][CH3:3].S(Cl)([Cl:19])=O>>[CH2:1]([S:4]([NH:7][C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11]([Cl:19])=[O:12])(=[O:6])=[O:5])[CH2:2][CH3:3]

Komponenten

Edukt 2

HCID 24386Thionyl Chloride

HCID 162282623-(Propane-1-sulfonamido)benzoic acid

Produkt 1

HCID 58087452HCID 58087452, Verbindung

Versuchsvorschrift

A solution of 3-(propane-1-sulfonylamino)-benzoic acid (76, 1.20 g, 4.93 mmol) in thionyl chloride was heated to reflux for 3.0 hours. Evaporation of the solvent gave compound 77 as white solid that was used for the next step.

Aufarbeitung

temperatureto reflux for 3.0 hours
customEvaporation of the solvent

Quellen und Nachweise

ORD-Eintrag: ord-acd0f00ba1ce45a1927d95672fbd4cef
Quelldatensatz: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08470818B2

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