Ammonium formate → thieno[3,4-d]pyrimidin-4(3H)-one

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A stirred mixture of methyl 4-formamido-3-thenoate (see below) (3.39 g) and ammonium formate (3.4 g) in formamde (5 ml) was heated at 140° C. for 7 hours. On cooling, the mixture was poured into water, and the mixture filtered to give a solid which was washed with water followed by light petroleum (b.p. 60-80° C.) and air dried to give the title product, m.p. 275-278° C.

Herkunft & Nachweise