Dimethylamine → 5-(Dimethylamino)pentanenitrile

HRID 1264298Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1264298
[CH3:1][NH:2][CH3:3].Br[CH2:5][CH2:6][CH2:7][CH2:8][C:9]#[N:10]>[OH-].[Na+]>[CH3:1][N:2]([CH3:3])[CH2:5][CH2:6][CH2:7][CH2:8][C:9]#[N:10]

Komponenten

4

Edukt 2

HCID 674DimethylamineHCID 794355-Bromopentanenitrile

Produkt 1

HCID 53056495-(Dimethylamino)pentanenitrile

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 14798Sodium HydroxideLösungsmittel

Versuchsvorschrift

A mixture of dimethylamine (4 mL, 40% in water) and 5-bromo-pentanenitrile (2.3 mL, 20 mmol) is stirred for 24 h. The resulting reaction mixture is diluted with sodium hydroxide solution (10 mL, 5M) and extracted with ether. The ether extract is dried over K2CO3 and concentrated under reduced pressure to give an oil (1.5 g) which is used without further purification.

Aufarbeitung

  1. customThe resulting reaction mixture
  2. extractionextracted with ether
  3. extractionThe ether extract
  4. dry with materialis dried over K2CO3
  5. concentrationconcentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-44a70acd3b3c45d787ed0e4e7e0076b1
Quelldatensatz
uspto-grants-2003_04
Patentnummer
US06541505B1

Notizen zur Reaktion

Wird geladen…