2-Bromo-1-(pentafluorophenyl)ethan-1-one → HCID 18613824, Verbindung
Reaktionsgleichung
[C:1]([C:4]1[CH:13]=[CH:12][C:7]([C:8]([O:10][CH3:11])=[O:9])=[CH:6][CH:5]=1)(=[S:3])[NH2:2].[F:14][C:15]1[C:24]([F:25])=[C:23]([F:26])[C:22]([F:27])=[C:21]([F:28])[C:16]=1[C:17](=O)[CH2:18]Br>>[F:14][C:15]1[C:24]([F:25])=[C:23]([F:26])[C:22]([F:27])=[C:21]([F:28])[C:16]=1[C:17]1[N:2]=[C:1]([C:4]2[CH:13]=[CH:12][C:7]([C:8]([O:10][CH3:11])=[O:9])=[CH:6][CH:5]=2)[S:3][CH:18]=1Komponenten
3
Versuchsvorschrift
In the same manner as in Example 28, methyl 4-thiocarbamoylbenzoate was reacted with 2,3,4,5,6-pentafluorophenacyl bromide to obtain methyl 4-[4-(2,3,4,5,6-pentafluorophenyl)-2-thiazolyl]benzoate. The product was recrystallized from ethanol. Yield: 60%. Pale yellow prisms. Melting point: 141 to 142° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-7913757938084c16b952af0405113729
- Quelldatensatz
- uspto-grants-2003_04