trans-2-Phenylcyclopropyl isocyanate → N-{4-[4-amino-2-(ethoxymethyl)-7-methyl-1H-imidazo[4,5-c]pyridin-1-yl]butyl}-N'-[(1R,2S)-2-phenylcyclopropyl]urea
Reaktionsgleichung
[C:1]1([C@@H:7]2[CH2:9][C@H:8]2[N:10]=[C:11]=[O:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:13][CH2:14][CH2:15][CH2:16][CH2:17][N:18]1[C:26]2[C:25]([CH3:27])=[CH:24][N:23]=[C:22]([NH2:28])[C:21]=2[N:20]=[C:19]1[CH2:29][O:30][CH2:31][CH3:32]>>[NH2:28][C:22]1[C:21]2[N:20]=[C:19]([CH2:29][O:30][CH2:31][CH3:32])[N:18]([CH2:17][CH2:16][CH2:15][CH2:14][NH:13][C:11]([NH:10][C@@H:8]3[CH2:9][C@H:7]3[C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)=[O:12])[C:26]=2[C:25]([CH3:27])=[CH:24][N:23]=1Komponenten
3
Versuchsvorschrift
Using the method of Examples 147-164, trans-2-phenylcyclopropyl isocyanate was reacted with 1-(4-aminobutyl)-2-(ethoxymethyl)-7-methyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 437.2668.
Quellen und Nachweise
- ORD-Eintrag
- ord-94ce317b2b2e4fba81ab55e50296a7ee