Stannous chloride dihydrate → Carbamic acid,[2-amino-4-cyano-5-[methyl(2-methylpropyl)amino]phenyl]-,1,1-dimethylethyl ester
Reaktionsgleichung
[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH2:16][CH:17]([CH3:19])[CH3:18])[CH3:15])[C:11]([C:20]#[N:21])=[CH:10][C:9]=1[N+:22]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH2:16][CH:17]([CH3:18])[CH3:19])[CH3:15])[C:11]([C:20]#[N:21])=[CH:10][C:9]=1[NH2:22])([CH3:3])([CH3:4])[CH3:2]Komponenten
3
Versuchsvorschrift
The title compound was prepared from [4-cyano-5-(isobutyl-methyl-amino)-2-nitro-phenyl]-carbamic acid tert-butyl ester (Example C29) (1.76 g, 5.05 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as a light brown solid (1.55 g, 96%).
Quellen und Nachweise
- ORD-Eintrag
- ord-a3eb82a7590243189abf30dd2756afe5
- Quelldatensatz
- uspto-grants-2003_04