2-Nitrophenol → HCID 7434133, Verbindung

Reaktionsgleichung

[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[OH:10])([O-:3])=[O:2].C(=O)([O-])[O-].[K+].[K+].[Cl:17][C:18]1[CH:19]=[C:20]([CH2:28]Cl)[C:21]2[O:26][CH2:25][O:24][CH2:23][C:22]=2[CH:27]=1>CC(C)=O>[Cl:17][C:18]1[CH:19]=[C:20]([CH2:28][O:10][C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N+:1]([O-:3])=[O:2])[C:21]2[O:26][CH2:25][O:24][CH2:23][C:22]=2[CH:27]=1

Komponenten

Versuchsvorschrift

To a solution of 2-nitrophenol (1.27 g, 9.13 mmol) in acetone (100 mL) was added solid potassium carbonate (1.27 g, 9.13 mmol) followed by 6-chloro-8-(chloromethyl)benzo-1,3-dioxan (1.0 g, 4.57 mmol) and the solution was refluxed for 16 hours. Solvent was evaporated and the residue was purified by column chromatography to give 1-[(6-chloro(2H,4H-benzo[e]1,3-dioxin-8-yl))methoxy]-2-nitrobenzene, a compound of formula (3).