4-Methyloxybenzyl chloride → N-(2,6-dimethylphenyl)-2-(4-{2-hydroxy-4-[4-(trifluoromethyl)phenyl]butyl}piperazinyl)acetamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-Methyloxybenzyl chloride	HCID 69993	—
Edukt	p-Trifluoromethylbenzyl chloride	HCID 123096	—
Edukt	N-(2,6-dimethylphenyl)-2-{4-[4-(4-methoxyphenyl)-2-hydroxybutyl]piperazinyl}acetamide	HCID 12052937	—
Produkt	N-(2,6-dimethylphenyl)-2-(4-{2-hydroxy-4-[4-(trifluoromethyl)phenyl]butyl}piperazinyl)acetamide	HCID 10276533	—

Reaktionsschritte

Compound 21 was prepared in a manner similar to that of compound 16 substituting 4-trifluoromethylbenzyl chloride for 4-methoxybenzyl chloride. (M+1)=464.2

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US06552023B2
Quelldatensatz	uspto-grants-2003_04
ORD ID	ord-eee3d3073cd4467aa6155cd9d0138417
Quellennotiz	uspto-grants-2003_04