4-Chlorophenylboronic acid → Ethyl 2-(4-chlorophenyl)isonicotinate
Reaktionsgleichung
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](B(O)O)=[CH:4][CH:3]=1.Cl[C:12]1[CH:13]=[C:14]([CH:20]=[CH:21][N:22]=1)[C:15]([O:17][CH2:18][CH3:19])=[O:16]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:12]2[CH:13]=[C:14]([CH:20]=[CH:21][N:22]=2)[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
4-Chlorophenylboronic acid (185 mg) and ethyl 2-chloroisonicotinate (200 mg) were reacted in the same manner as in Preparation Example 1 to obtain the title compound.
Quellen und Nachweise
- ORD-Eintrag
- ord-c09ba5e6659f456f82c99572ebe8fa3f
- Quelldatensatz
- uspto-grants-2003_04
- Patentnummer
- US06552188B2
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