4-Nitroaniline → N-(4-nitrophenyl)-3-chloropropane-1-sulfonamide

HRID 1268817Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1268817
[N+:1]([C:4]1[CH:10]=[CH:9][C:7]([NH2:8])=[CH:6][CH:5]=1)([O-:3])=[O:2].[Cl:11][CH2:12][CH2:13][CH2:14][S:15](Cl)(=[O:17])=[O:16]>N1C=CC=CC=1>[N+:1]([C:4]1[CH:10]=[CH:9][C:7]([NH:8][S:15]([CH2:14][CH2:13][CH2:12][Cl:11])(=[O:17])=[O:16])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Komponenten

4

Edukt 2

HCID 74754-NitroanilineHCID 154103-Chloropropanesulphonyl chloride

Produkt 1

HCID 17988807N-(4-nitrophenyl)-3-chloropropane-1-sulfonamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

A solution of 5.00 g (36.2 mmol) of 4-nitroaniline and 6.41 g (36.2 mmol) of 3-chloropropanesulfonyl chloride in 20 ml of pyridine is stirred overnight at room temperature. The reaction mixture is then poured onto ice. The precipitate which deposits in the process is filtered off with suction and dried, giving N-(4-nitrophenyl)-3-chloropropane-1-sulfonamide as a yellowish solid; ESI 279.

Aufarbeitung

  1. additionThe reaction mixture is then poured onto ice
  2. filtrationis filtered off with suction
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-dad8a22826ee4ef1ae0115a041e9ed1e
Quelldatensatz
uspto-grants-2007_04
Patentnummer
US07199133B2

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