6-methyl-1H-indazol-5-ol → 6-methyl-5-(piperidin-4-yloxy)-1H-indazole

HRID 1269824

Reaktionsgleichung

Reaktionsgleichung von HRID 1269824
C(OC1C=C2[C:11](=[CH:12][C:13]=1C)[N:10]([C:15](=O)[CH3:16])N=C2)(=O)C.[CH3:18][C:19]1[CH:27]=[C:26]2[C:22]([CH:23]=[N:24][NH:25]2)=[CH:21][C:20]=1[OH:28]>>[CH3:18][C:19]1[CH:27]=[C:26]2[C:22]([CH:23]=[N:24][NH:25]2)=[CH:21][C:20]=1[O:28][CH:13]1[CH2:12][CH2:11][NH:10][CH2:15][CH2:16]1

Komponenten

3

Edukt 2

HCID 229340186-methyl-1H-indazol-5-olHCID 694307581-acetyl-6-methyl-1H-indazol-5-yl acetate

Produkt 1

HCID 229335796-methyl-5-(piperidin-4-yloxy)-1H-indazole

Versuchsvorschrift

The following compound of Example 406 was synthesized by carrying out reactions according to the methods described in Example 372, (b) and Example 377, except for using the 6-methyl-1H-indazol-5-ol synthesized in Example 403, as a starting material.

Quellen und Nachweise

ORD-Eintrag
ord-4ff30137941c4520b6dac0ea2e01445b
Quelldatensatz
uspto-grants-2007_04
Patentnummer
US07199147B2

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