HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → 4-(2-Pyridyl)-4-oxo-2-butenoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | 4-(2-Pyridyl)-4-oxo-2-butenoic acid, methyl ester | HCID 86737542 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | 4-(2-Pyridyl)-4-oxo-2-butenoic acid | HCID 54111695 | — |
Reaktionsschritte
A mixture of 15 g of 4-(2-pyridyl)-4-oxo-2-butenoic acid, methyl ester in chloroform (50 ml) is stirred with 3.14 g of sodium hydroxide in 50 ml of water for 5 hours at room temperature. The aqueous layer is separated, washed with chloroform and acidified with 4.71 g of acetic acid, yielding the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04254267 |
| Quelldatensatz | uspto-grants-1981_03 |
| ORD ID | ord-aa0ab47e1815402481c8ae032491d1c9 |
| Quellennotiz | uspto-grants-1981_03 |