4,5-Di-p-tolyl-2-(methylamino)pyrimidine → 2-{4-[N-(4,5-di-p-tolylpyrimidin-2-yl)-N-methylamino]butyloxy}acetic Acid Tert-Butyl Ester
Reaktionsgleichung
[C:1]1([CH3:22])[CH:6]=[CH:5][C:4]([C:7]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=3)=[CH:11][N:10]=[C:9]([NH:20][CH3:21])[N:8]=2)=[CH:3][CH:2]=1.[C:23]([O:27][C:28](=[O:36])[CH2:29][O:30][CH2:31][CH2:32][CH2:33][CH2:34]Br)([CH3:26])([CH3:25])[CH3:24]>>[C:23]([O:27][C:28](=[O:36])[CH2:29][O:30][CH2:31][CH2:32][CH2:33][CH2:34][N:20]([C:9]1[N:8]=[C:7]([C:4]2[CH:3]=[CH:2][C:1]([CH3:22])=[CH:6][CH:5]=2)[C:12]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=2)=[CH:11][N:10]=1)[CH3:21])([CH3:26])([CH3:25])[CH3:24]Komponenten
3
Versuchsvorschrift
In the same manner as in Example 22, except that 4,5-di-p-tolyl-2-(methylamino)pyrimidine was used in place of 5,6-diphenyl-2-(methylamino)pyrazine and 2-(4-bromobutyloxy)acetic acid tert-butyl ester was used in place of 2-(4-bromobutyloxy)acetic acid methyl ester, the desired compound was prepared as a pale yellow oily substance.
Quellen und Nachweise
- ORD-Eintrag
- ord-f2b89caa543e49e9862bb469ba76c4f0
- Quelldatensatz