(R)-2-azido-1-benzylethylamine → (2R)-3-Phenylpropane-1,2-diamine

Beteiligte Stoffe

Reaktionsschritte

A sample of the compound from step 164d (1.2 g, 6.8 mmol) was hydrogenated (4 atm) in ethanol over 1.2 g of 10% Pd/C for 21.5 hours at room temperature. The mixture was filtered to remove the catalyst, and the solvent was removed to afford the title compound (1.055 g). MS m/z (M+H)+: 151, MS m/z (M+NH4)+: 168.

Herkunft & Nachweise