HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(Allyl)pyrrolidine-2-methylamine → N-(1-allyl-2-pyrrolidylmethyl)-7-methylsulfamoyl-1,4-benzodioxane-5-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(Allyl)pyrrolidine-2-methylamine | HCID 117296 | — |
| Edukt | 7-Methylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride | HCID 20544720 | — |
| Produkt | N-(1-allyl-2-pyrrolidylmethyl)-7-methylsulfamoyl-1,4-benzodioxane-5-carboxamide | HCID 24834937 | 52,6% |
Reaktionsschritte
In a similar manner to the above example, 84 g of dextrorotatory 1-allyl-2-aminomethyl-pyrrolidine was reacted with 175 g of 7-methylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride to give, after purification, 125 g of dextrorotatory-N-(1-allyl-2-pyrrolidylmethyl)-7-methylsulfamoyl-1,4-benzodioxane-5-carboxamide (M.P.: 104°-105° C.; yield: 52.6%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04255580 |
| Quelldatensatz | uspto-grants-1981_03 |
| ORD ID | ord-fca742a7467a47eba581965654bdf0a0 |
| Quellennotiz | uspto-grants-1981_03 |