HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Methylpyrrolidine-2-methylamine → N-(1-methyl-2-pyrrolidylmethyl)-7-methylsulfamoyl-1,4-benzodioxane-5-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Methylpyrrolidine-2-methylamine | HCID 117300 | — |
| Edukt | 7-Methylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride | HCID 20544720 | — |
| Produkt | N-(1-methyl-2-pyrrolidylmethyl)-7-methylsulfamoyl-1,4-benzodioxane-5-carboxamide | HCID 24834936 | 77% |
Reaktionsschritte
In a similar manner to that of the above example, 71 g of levorotatory 1-methyl-2-aminomethyl-pyrrolidine was reacted with 180.5 g of 7-methylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride to give 175 g of levorotatory-N-(1-methyl-2-pyrrolidylmethyl)-7-methylsulfamoyl-1,4-benzodioxane-5-carboxamide (M.P.: 187°-187.5° C.; yield: 77%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04255580 |
| Quelldatensatz | uspto-grants-1981_03 |
| ORD ID | ord-772f9aff10c54927bf8ad6f38c6f8246 |
| Quellennotiz | uspto-grants-1981_03 |