4-Iodophenylacetate → 4-[3-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)-1-propynyl]phenyl acetate
Reaktionsgleichung
[C:1]([CH:3]([C:5]1[C:14]([CH3:15])=[CH:13][C:12]2[C:11]([CH3:17])([CH3:16])[CH2:10][CH2:9][C:8]([CH3:19])([CH3:18])[C:7]=2[CH:6]=1)[OH:4])#[CH:2].[C:20]([O:23][C:24]1[CH:29]=[CH:28][C:27](I)=[CH:26][CH:25]=1)(=[O:22])[CH3:21]>>[C:20]([O:23][C:24]1[CH:29]=[CH:28][C:27]([C:2]#[C:1][CH:3]([OH:4])[C:5]2[C:14]([CH3:15])=[CH:13][C:12]3[C:11]([CH3:17])([CH3:16])[CH2:10][CH2:9][C:8]([CH3:19])([CH3:18])[C:7]=3[CH:6]=2)=[CH:26][CH:25]=1)(=[O:22])[CH3:21]Komponenten
3
Versuchsvorschrift
Following the basic procedure of Example 11(d), by reacting 1.28 g (5 mmol) of α-ethynyl-5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenemethanol with 1.44 g (5,5 mmol) of 4-iodophenyl acetate, 480 mg (25%) of the expected compound, with a melting point of 129°-130° C., were obtained.
Quellen und Nachweise
- ORD-Eintrag
- ord-32748febd8d84cee86f2313b328c7462
- Quelldatensatz
- uspto-grants-2000_12
- Patentnummer
- US06162445
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