N-bromobutanimide → 2-Bromomethyl-8-methyl-5H-dibenzo[a,d]cyclohepten-5-one

HRID 1275902Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1275902
[CH3:1][C:2]1[CH:18]=[CH:17][C:5]2[C:6](=[O:16])[C:7]3[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][C:8]=3[CH:9]=[CH:10][C:4]=2[CH:3]=1.[Br:19]N1C(=O)CCC1=O>C(OCC)(=O)C>[Br:19][CH2:1][C:2]1[CH:18]=[CH:17][C:5]2[C:6](=[O:16])[C:7]3[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][C:8]=3[CH:9]=[CH:10][C:4]=2[CH:3]=1

Komponenten

4

Edukt 2

HCID 67184N-bromobutanimideHCID 221172592,8-dimethyl-5H-dibenzo[a,d][7]annulen-5-one

Produkt 1

HCID 221172722-Bromomethyl-8-methyl-5H-dibenzo[a,d]cyclohepten-5-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

The product of step (i) (2.0 g) and N-bromosuccinimide (1.52 g) in ethyl acetate (80ml) was irradiated with a 500 W halogen lamp for 4 hours. The reaction mixture was washed with brine, dried (MgSO4) and evaporated under reduced pressure. Purification was by chromatography eluting with toluene. Used directly in the next step.

Aufarbeitung

  1. washThe reaction mixture was washed with brine
  2. dry with materialdried (MgSO4)
  3. customevaporated under reduced pressure
  4. customPurification
  5. washeluting with toluene

Quellen und Nachweise

ORD-Eintrag
ord-4d603e7f5bba488d825ad0603cbf16b3
Quelldatensatz
uspto-grants-2000_12
Patentnummer
US06162808

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