Acetone → 3-(Methylsulfonyl)benzenesulfonamide

HRID 1276524Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1276524
CS[C:3]1[CH:4]=[C:5]([S:9]([NH2:12])(=[O:11])=[O:10])[CH:6]=[CH:7][CH:8]=1.OO[S:15]([O-:17])=[O:16].[K+].[CH3:19]C(C)=O>>[CH3:19][S:15]([C:7]1[CH:6]=[C:5]([S:9]([NH2:12])(=[O:11])=[O:10])[CH:4]=[CH:3][CH:8]=1)(=[O:17])=[O:16]

Komponenten

4

Edukt 3

HCID 180AcetoneHCID 18461638HCID 18461638, VerbindungHCID 23707502Potassium hydroxy sulfite

Produkt 1

HCID 136682473-(Methylsulfonyl)benzenesulfonamide

Versuchsvorschrift

To a solution of 3-methylsulfanylbenzenesulfonamide (500 mg, 2.5 mmol) in acetone was added an aqueous solution of OXONE (3.2 grams, 5 mmol). The mixture was stirred at room temperature for 12 hours. The reaction was evaporated to dryness in vacuo. The residue was triturated with acetone and filtered. The filtrated was evaporated to give 460 mg of the titled compound.

Aufarbeitung

  1. customThe reaction was evaporated to dryness in vacuo
  2. customThe residue was triturated with acetone
  3. filtrationfiltered
  4. customThe filtrated was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-e03dc7965cad4f6bac233f4eed9e81e8
Quelldatensatz
uspto-grants-2000_12
Patentnummer
US06166064

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