HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → 3-Isoxazolamine, 5-(1,1-dimethylethyl)-
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Pentanenitrile, 4,4-dimethyl-3-oxo- | HCID 108871 | — |
| Edukt | Hydroxylamine, sulfate (1:1) | HCID 159255 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 3-Isoxazolamine, 5-(1,1-dimethylethyl)- | HCID 171473 | 81,7% |
Reaktionsschritte
A suspension of pivaloylacetonitrile (12.52 g) and triethylamine (11.27 g) in water (200 ml) is stirred and mixed with hydroxylamine sulfate (9.03 g). pH 8.22. The reaction mixture is treated as in Example 2 to give 3-amino-5-t-butylisoxazole (11.45 g; yield, 81.7%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04256899 |
| Quelldatensatz | uspto-grants-1981_03 |
| ORD ID | ord-d73c023895844ceaa0b5ec960b928bde |
| Quellennotiz | uspto-grants-1981_03 |