Acetonitrile → (3,4,5-Trimethyl-2-thenyl)-triphenyl phosphonium bromide

HRID 127740

Reaktionsgleichung

Reaktionsgleichung von HRID 127740
O[CH2:2][C:3]1[S:4][C:5]([CH3:10])=[C:6]([CH3:9])[C:7]=1[CH3:8].C(#N)C.[Br-:14].[C:15]1([PH+:21]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C(OCC)(=O)C>[Br-:14].[CH3:8][C:7]1[C:6]([CH3:9])=[C:5]([CH3:10])[S:4][C:3]=1[CH2:2][P+:21]([C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)([C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Komponenten

5

Edukt 3

HCID 6342AcetonitrileHCID 517696Phosphine, triphenyl-, hydrobromideHCID 128752592-Hydroxymethyl-3,4,5-trimethyl-thiophene

Produkt 1

HCID 20285709(3,4,5-Trimethyl-2-thenyl)-triphenyl phosphonium bromide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

2.2 G. of 2-hydroxymethyl-3,4,5-trimethyl-thiophene were dissolved in 25 ml. of acetonitrile and 4.6 g. of triphenylphosphonium bromide were added. The resulting reaction mixture was heated to 50° C. for 3 hours. After evaporation of the solvent, the residue which formed was diluted with ethyl acetate, heated briefly and filtered. The crystalline (3,4,5-trimethyl-2-thenyl)-triphenyl phosphonium bromide obtained was dried at 50° C. under high vacuum and had m.p. 208°-215° C.

Aufarbeitung

  1. customThe resulting reaction mixture
  2. customAfter evaporation of the solvent
  3. customthe residue which formed
  4. temperatureheated briefly
  5. filtrationfiltered

Quellen und Nachweise

ORD-Eintrag
ord-cd04a7b7bc634cb48bc21871ad5272e3
Quelldatensatz
uspto-grants-1981_03
Patentnummer
US04256878

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