2-Amino-5-(trifluoromethyl)pyridine → 1-(2-Chloro-6-fluorobenzoyl)-3-(5-trifluoromethyl-2-pyridinyl)urea

HRID 1278179Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1278179
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:4]=[CH:5][C:6]([NH2:9])=[N:7][CH:8]=1.[Cl:12][C:13]1[CH:23]=[CH:22][CH:21]=[C:20]([F:24])[C:14]=1[C:15]([N:17]=[C:18]=[O:19])=[O:16]>>[Cl:12][C:13]1[CH:23]=[CH:22][CH:21]=[C:20]([F:24])[C:14]=1[C:15]([NH:17][C:18]([NH:9][C:6]1[CH:5]=[CH:4][C:3]([C:2]([F:1])([F:10])[F:11])=[CH:8][N:7]=1)=[O:19])=[O:16]

Komponenten

3

Edukt 2

HCID 7358622-Amino-5-(trifluoromethyl)pyridineHCID 130517312-Chloro-6-fluorobenzoyl isocyanate

Produkt 1

HCID 205331381-(2-Chloro-6-fluorobenzoyl)-3-(5-trifluoromethyl-2-pyridinyl)urea

Versuchsvorschrift

A portion of 5-trifluoromethyl-2-aminopyridine is reacted with 2-chloro-6-fluorobenzoyl isocyanate as described in Example 1. The reaction mixture is evaporated under vacuum and the product is recrystallized to obtain the product named above.

Aufarbeitung

  1. customThe reaction mixture is evaporated under vacuum
  2. customthe product is recrystallized
  3. customto obtain the product

Quellen und Nachweise

ORD-Eintrag
ord-e5930e012c074200becefce690fb7738
Quelldatensatz
uspto-grants-1981_07
Patentnummer
US04281003

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