2-(1-Methoxyethyl)-3-benzyloxy-6-methyl-pyran-4(1H)-one → 1,6-dimethyl-2-(1-methoxyethyl)-3-benzyloxy-pyridin-4(1H)-one hydrochloride
Reaktionsgleichung
[ClH:1].[CH3:2][N:3]1[C:8]([CH3:9])=[CH:7][C:6](=[O:10])[C:5]([O:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[C:4]1[CH2:19][O:20][CH3:21].[CH3:22]OC(C1OC(C)=CC(=O)C=1OCC1C=CC=CC=1)C>>[ClH:1].[CH3:2][N:3]1[C:8]([CH3:9])=[CH:7][C:6](=[O:10])[C:5]([O:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[C:4]1[CH:19]([O:20][CH3:21])[CH3:22]Komponenten
3
Versuchsvorschrift
The title compound was prepared by the method outlined for 1,6-dimethyl-2-methoxymethyl-3-benyloxy-pyridin-4(1H)-one hydrochloride, using 3.56 g (13 mmol, 1 eq.) of 2-(1-methoxyethyl)-3-benzyloxy-6-methyl-pyran-4(1H)-one to yield the pure product 2.64 g (62.8%) after recrystallisation from methanol/diethyl ether, as a white crystalline solid m.p 17-19° C.
Quellen und Nachweise
- ORD-Eintrag