4-Chlorobenzenesulfonyl chloride → Ethyl 2-{4-[2-(4-chlorobenzenesulphonylamino)-ethyl]-phenoxy}-2-methylpropionate
Reaktionsgleichung
[NH2:1][CH2:2][CH2:3][C:4]1[CH:18]=[CH:17][C:7]([O:8][C:9]([CH3:16])([CH3:15])[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:6][CH:5]=1.[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([S:26](Cl)(=[O:28])=[O:27])=[CH:22][CH:21]=1>>[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([S:26]([NH:1][CH2:2][CH2:3][C:4]2[CH:5]=[CH:6][C:7]([O:8][C:9]([CH3:15])([CH3:16])[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:17][CH:18]=2)(=[O:28])=[O:27])=[CH:22][CH:21]=1Komponenten
3
Versuchsvorschrift
By the reaction of ethyl 2-[4-(2-aminoethyl)-phenoxy]-2-methylpropionate with 4-chlorobenzenesulphonyl chloride in a manner analogous to that described in Example 2, there is obtained, in a yield of 69% of theory, colorless ethyl 2-{4-[2-(4-chlorobenzenesulphonylamino)-ethyl]-phenoxy}-2-methylpropionate in the form of a viscous oil. From this there is obtained, by hydrolysis:
Quellen und Nachweise
- ORD-Eintrag