HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-(2-phenyl-phenylmethyl)-phthalimide → 1-Biphenyl-2-ylmethanamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-(2-phenyl-phenylmethyl)-phthalimide | HCID 18426122 | — |
| Lösungsmittel | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Produkt | 1-Biphenyl-2-ylmethanamine | HCID 263366 | 78,9% |
Reaktionsschritte
N-(2-Phenyl-phenylmethyl)-phthalimide (6.5 g) in 25 cc of hydrazine hydrate were stirred at room temperature overnight. Ice water was added and the solid separated by filtration. The filtrate was salted out with brine and extracted with ethyl acetate. The ethyl acetate extract was washed with water, dried over magnesium sulfate, filtered and concentrated to dryness to afford 3 g of subtitled product as an oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06451839B1 |
| Quelldatensatz | uspto-grants-2002_09 |
| ORD ID | ord-92513ac2ba0f4915b383c24c79517d71 |
| Quellennotiz | uspto-grants-2002_09 |