2-Bromo-4-chloro-6-fluoroaniline → N,N-dimethyl-5-ethyl-2-(2'-bromo-4'-chloro-6'-fluoroanilino)phenylacetamide
Reaktionsgleichung
[CH3:1][N:2]([CH3:15])[C:3](=[O:14])[CH2:4][C:5]1[CH:10]=[C:9]([CH2:11][CH3:12])[CH:8]=[CH:7][C:6]=1I.[Br:16][C:17]1[CH:23]=[C:22]([Cl:24])[CH:21]=[C:20]([F:25])[C:18]=1[NH2:19]>>[CH3:1][N:2]([CH3:15])[C:3](=[O:14])[CH2:4][C:5]1[CH:10]=[C:9]([CH2:11][CH3:12])[CH:8]=[CH:7][C:6]=1[NH:19][C:18]1[C:20]([F:25])=[CH:21][C:22]([Cl:24])=[CH:23][C:17]=1[Br:16]Komponenten
3
Versuchsvorschrift
Ullmann condensation of N,N-dimethyl-5-ethyl-2-iodo-phenylacetamide with 2-bromo-4-chloro-6-fluoroaniline according to the procedure described in Example 1 yields N,N-dimethyl-5-ethyl-2-(2′-bromo-4′-chloro-6′-fluoroanilino)phenylacetamide.
Quellen und Nachweise
- ORD-Eintrag
- ord-62736c82ce3d40a786ec28b1d2410f8b
- Quelldatensatz
- uspto-grants-2002_09