2-Piperazinylpyrimidine dihydrochloride → HCID 70034524, Verbindung
Reaktionsgleichung
[ClH:1].Cl.[N:3]1[CH:8]=[CH:7][CH:6]=[N:5][C:4]=1[N:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1.[Cl:15][CH:16]([C:18]1[CH:23]=[CH:22][C:21]([CH2:24][NH:25][C:26](=[O:28])[CH3:27])=[CH:20][CH:19]=1)[CH3:17]>>[ClH:15].[ClH:1].[N:3]1[CH:8]=[CH:7][CH:6]=[N:5][C:4]=1[N:9]1[CH2:14][CH2:13][N:12]([CH:16]([C:18]2[CH:23]=[CH:22][C:21]([CH2:24][NH:25][C:26](=[O:28])[CH3:27])=[CH:20][CH:19]=2)[CH3:17])[CH2:11][CH2:10]1Komponenten
3
Versuchsvorschrift
By similar reaction and treatment to that in Example 1(5) using 1-(2-pyrimidyl) piperazine dihydrochloride instead of phenylpiperazine and N-(4-(1-chloroethyl)phenylmethyl)acetamide instead of N-(4-chloromethylphenylmethyl) acetamide, the title compound was obtained as a yellow amorphous solid.
Aufarbeitung
- customBy similar reaction and treatment to that in Example
Quellen und Nachweise
- ORD-Eintrag
- ord-ec8d4f439dd0446b8e107448eda28dc5