[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[N:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1.Cl[CH:13]([C:15]1[CH:20]=[CH:19][C:18]([CH2:21][NH:22][C:23](=[O:25])[CH3:24])=[CH:17][CH:16]=1)[CH3:14]>>[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[N:6]1[CH2:7][CH2:8][N:9]([CH:13]([C:15]2[CH:20]=[CH:19][C:18]([CH2:21][NH:22][C:23](=[O:25])[CH3:24])=[CH:17][CH:16]=2)[CH3:14])[CH2:10][CH2:11]1By similar reaction and treatment to that in Example 1(5) using 1-(2-thiazolyl)piperazine instead of phenylpiperazine and N-(4-(1-chloroethyl)phenylmethyl)acetamide instead of N-(4-chloromethylphenylmethyl) acetamide, the title compound was obtained as a brown oil.
Wird geladen…