Ethyl isocyanate → 1-Butyl-3-ethyl-1-(4-methyl-2-oxazolyl)urea

HRID 128230

Reaktionsgleichung

Reaktionsgleichung von HRID 128230
[CH2:1]([NH:5][C:6]1[O:7][CH:8]=[C:9]([CH3:11])[N:10]=1)[CH2:2][CH2:3][CH3:4].[CH2:12]([N:14]=[C:15]=[O:16])[CH3:13]>C1C=CC=CC=1>[CH2:1]([N:5]([C:6]1[O:7][CH:8]=[C:9]([CH3:11])[N:10]=1)[C:15]([NH:14][CH2:12][CH3:13])=[O:16])[CH2:2][CH2:3][CH3:4]

Komponenten

4

Edukt 2

HCID 8022Ethyl isocyanateHCID 122952262-Oxazolamine, N-butyl-4-methyl-

Produkt 1

HCID 234689611-Butyl-3-ethyl-1-(4-methyl-2-oxazolyl)urea

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

A solution of 2-butylamino-4-methyloxazole (15.0 g, 0.0972 mol) and ethyl isocyanate (7.6 g, 0.107 mol) in dry benzene was heated under reflux for 2 hours and then evaporated to dryness. The residual oil was dissolved in ether and the solution was washed with 2 N HCl, dried and evaporated. The residue was distilled under vacuum b.p. 128° C./1.0 mm. IR 3275, 1696, 1590 cm-1.

Aufarbeitung

  1. temperatureunder reflux for 2 hours
  2. customevaporated to dryness
  3. dissolutionThe residual oil was dissolved in ether
  4. washthe solution was washed with 2 N HCl
  5. customdried
  6. customevaporated
  7. distillationThe residue was distilled under vacuum b.p. 128° C./1.0 mm

Quellen und Nachweise

ORD-Eintrag
ord-301688ca646241a0ac49c29f06d174f1
Quelldatensatz
uspto-grants-1981_03
Patentnummer
US04259343

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