Potassium Hydroxide → 3-[3-(4-anilinoanilino)-3-oxopropyl]sulfanyl-N-(4-anilinophenyl)propanamide

HRID 1283481Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1283481
[NH:1]([C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:19])[CH2:16][CH2:17][SH:18])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-:20].[K+]>C(O)C>[NH:1]([C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:19])[CH2:16][CH2:17][S:18][CH2:17][CH2:16][C:15]([NH:14][C:11]2[CH:12]=[CH:13][C:8]([NH:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)=[CH:9][CH:10]=2)=[O:20])=[CH:10][CH:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

4

Edukt 2

HCID 14797Potassium HydroxideHCID 19795022N-(4-Anilinophenyl)-3-sulfanylpropanamide

Produkt 1

HCID 41683323-[3-(4-anilinoanilino)-3-oxopropyl]sulfanyl-N-(4-anilinophenyl)propanamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel2×

Versuchsvorschrift

To a suspension of 20.4 grams of N-4(anilinophenyl)acrylamide in 200 milliliters of ethanol was added 23.3 grams of N-(4-anilinophenyl)-3-mercaptopropionamide. A solution of one gram of potassium hydroxide in 10 milliliters of ethanol was added at 17.5°C. Within a few minutes the temperature began to rise, reaching a maximum of 28°C. Simultaneous with the increase in temperature, product began to precipitate. The reaction mixture was stirred for 2 hours. The solid product was filtered off and allowed to dry. There was obtained 41 grams (94 percent of theory) of product which melted at 199°-203°C.

Aufarbeitung

  1. waitWithin a few minutes the temperature began
  2. customa maximum of 28°C
  3. temperatureSimultaneous with the increase in temperature, product
  4. customto precipitate
  5. filtrationThe solid product was filtered off
  6. customto dry
  7. customThere was obtained 41 grams (94 percent of theory) of product which melted at 199°-203°C.

Quellen und Nachweise

ORD-Eintrag
ord-435a0d474d28445cba4130d3d999b98a
Quelldatensatz
uspto-grants-1976_08
Patentnummer
US03975414

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