Sulfuric Acid → 1-Ethyl-4-(4-fluorophenyl)benzene

HRID 1283632Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1283632
C(C1C=CC(C2C=CC=CC=2F)=CC=1)#C.[C:16]([C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH:29]=[CH:28][C:27]([F:30])=[CH:26][CH:25]=2)=[CH:20][CH:19]=1)#[CH:17].S(=O)(=O)(O)O.[H][H]>>[CH2:16]([C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH:29]=[CH:28][C:27]([F:30])=[CH:26][CH:25]=2)=[CH:20][CH:19]=1)[CH3:17]

Komponenten

5

Edukt 4

HCID 1118Sulfuric AcidHCID 42040FluretofeneHCID 196905164-Ethynyl-4'-fluoro-1,1'-biphenylHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 214329111-Ethyl-4-(4-fluorophenyl)benzene

Versuchsvorschrift

The procedure of Example 1 was repeated, except that the 1-ethynyl-4-(2-fluorophenyl)benzene was replaced with 1.5 g. of 1-ethynyl 4-(4-fluorophenyl)benzene, the amount of catalyst was reduced to 0.5 g., the sulfuric acid was omitted, initial hydrogen pressure was 48 psig., and the reduction was allowed to proceed overnight. Evaporation of the benzene left a solid which was recrystallized from hexane to give 1-ethyl-4-(4-fluorophenyl)benzene, mp 60°-63°. The following elemental analysis was obtained:

Aufarbeitung

  1. customEvaporation of the benzene
  2. waitleft a solid which
  3. customwas recrystallized from hexane

Quellen und Nachweise

ORD-Eintrag
ord-39e593bb577a4889889825cdb36056b4
Quelldatensatz
uspto-grants-1976_08
Patentnummer
US03975543

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