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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1285007Erstellt: 26. Oktober 2026

(S)-1-benzyloxycarbonyl-N-[3-(2-oxo-pyrrolidinyl)propyl]-2-pyrrolidine carboxamide → (S)-N-[3-(2-oxo-1-pyrrolidinyl)propyl]-2-pyrrolidinecarboxamide

https://huagongshe.com/reaction/1285007

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(S)-1-benzyloxycarbonyl-N-[3-(2-oxo-pyrrolidinyl)propyl]-2-pyrrolidine carboxamideHCID 18601121—
KatalysatorHCID 178418390HCID 178418390—
LösungsmittelMethanolHCID 887—
Produkt(S)-N-[3-(2-oxo-1-pyrrolidinyl)propyl]-2-pyrrolidinecarboxamideHCID 5395867471,9%

Reaktionsschritte

In 150 ml of methanol was dissolved 4.32 g of compound (99) and the compound was hydrogenated using 432 mg of 10% palladium-carbon as a catalyst. Then, the catalyst was filtered off from the reaction mixture and the filtrate was concentrated to provide 1.99 g of (S)-N-[3-(2-oxo-1-pyrrolidinyl)propyl]-2-pyrrolidinecarboxamide (100).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04564609
Quelldatensatzuspto-grants-1986_01
ORD IDord-ce61d1d8367c4211bc70a45686c8eb50
Quellennotizuspto-grants-1986_01